# Trade Mark Journal No.2026/008 20 February 2026

## WO0000001900099 (42)

Office of origin: United States of America

Date of International Registration:20 December 2025
Date of designation in the UK: 20 December 2025

International priority date claimed: 10 September 2025 (United States of America) (99384441)

Class 42
  Providing an online non-downloadable computer software platform utilizing artificial intelligence and computational modeling technologies for use in the discovery and development of medical drugs targeting disordered proteins, the administration, management, and operation of molecular dynamics simulations, the conformational ensemble modeling of disordered protein structures, the computational docking of biomolecules against protein conformational ensembles, and the in silico screening and optimization of therapeutics, all of the foregoing in the fields of neurodegeneration, oncology and metabolic disease.

Topos Bio, Inc.

Representative: Kristin S. Cornuelle Orrick, Herrington & Sutcliffe LLP, 2050 Main Street, Suite 1100, Irvine CA 92614, UNITED STATES OF AMERICA